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Priming Is Dispensable for NLRP3 Inflammasome Activation in Human Monocytes In Vitro
Interleukin (IL)-18 and IL-1β are potent pro-inflammatory cytokines that contribute to inflammatory conditions such as rheumatoid arthritis and Alzheimer’s disease. They are produced as inactive precursors that are activated by large macromolecular complexes called inflammasomes upon sensing damage...
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| Publié dans: | Front Immunol |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7555430/ https://ncbi.nlm.nih.gov/pubmed/33101286 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.565924 |
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