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NLRP3-Inflammasome Activating DAMPs Stimulate an Inflammatory Response in Glia in the Absence of Priming Which Contributes to Brain Inflammation after Injury

Inflammation in the absence of infection (sterile inflammation) contributes to acute injury and chronic disease. Cerebral ischemia is a devastating condition in which the primary injury is caused by reduced blood supply and is therefore sterile. The cytokine interleukin-1β (IL-1β) is a key contribut...

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Bibliografske podrobnosti
Main Authors: Savage, Catherine Diane, Lopez-Castejon, Gloria, Denes, Adam, Brough, David
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Research Foundation 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3444764/
https://ncbi.nlm.nih.gov/pubmed/23024646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00288
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