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NLRP3-Inflammasome Activating DAMPs Stimulate an Inflammatory Response in Glia in the Absence of Priming Which Contributes to Brain Inflammation after Injury

Inflammation in the absence of infection (sterile inflammation) contributes to acute injury and chronic disease. Cerebral ischemia is a devastating condition in which the primary injury is caused by reduced blood supply and is therefore sterile. The cytokine interleukin-1β (IL-1β) is a key contribut...

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Detalhes bibliográficos
Main Authors: Savage, Catherine Diane, Lopez-Castejon, Gloria, Denes, Adam, Brough, David
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3444764/
https://ncbi.nlm.nih.gov/pubmed/23024646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00288
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