NLRP3-Inflammasome Activating DAMPs Stimulate an Inflammatory Response in Glia in the Absence of Priming Which Contributes to Brain Inflammation after Injury

Inflammation in the absence of infection (sterile inflammation) contributes to acute injury and chronic disease. Cerebral ischemia is a devastating condition in which the primary injury is caused by reduced blood supply and is therefore sterile. The cytokine interleukin-1β (IL-1β) is a key contribut...

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Autors principals: Savage, Catherine Diane, Lopez-Castejon, Gloria, Denes, Adam, Brough, David
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Research Foundation 2012
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3444764/
https://ncbi.nlm.nih.gov/pubmed/23024646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00288
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