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Chloride regulates dynamic NLRP3-dependent ASC oligomerization and inflammasome priming
The NLRP3 inflammasome is an important regulator of inflammation and immunity. It is a multimolecular platform formed within cells that facilitates the activation of proinflammatory caspases to drive secretion of cytokines such as interleukin-1β (IL-1β). Knowledge of the mechanisms regulating format...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6176575/ https://ncbi.nlm.nih.gov/pubmed/30232264 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1812744115 |
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