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USP7 and USP47 deubiquitinases regulate NLRP3 inflammasome activation

The assembly and activation of the inflammasomes are tightly regulated by post‐translational modifications, including ubiquitin. Deubiquitinases (DUBs) counteract the addition of ubiquitin and are essential regulators of immune signalling pathways, including those acting on the inflammasome. How DUB...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:EMBO Rep
Main Authors: Palazón‐Riquelme, Pablo, Worboys, Jonathan D, Green, Jack, Valera, Ana, Martín‐Sánchez, Fatima, Pellegrini, Carolina, Brough, David, López‐Castejón, Gloria
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6172458/
https://ncbi.nlm.nih.gov/pubmed/30206189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201744766
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