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USP7 and USP47 deubiquitinases regulate NLRP3 inflammasome activation

The assembly and activation of the inflammasomes are tightly regulated by post‐translational modifications, including ubiquitin. Deubiquitinases (DUBs) counteract the addition of ubiquitin and are essential regulators of immune signalling pathways, including those acting on the inflammasome. How DUB...

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Detalles Bibliográficos
Publicado en:EMBO Rep
Main Authors: Palazón‐Riquelme, Pablo, Worboys, Jonathan D, Green, Jack, Valera, Ana, Martín‐Sánchez, Fatima, Pellegrini, Carolina, Brough, David, López‐Castejón, Gloria
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6172458/
https://ncbi.nlm.nih.gov/pubmed/30206189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201744766
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