The NLRP3–inflammasome as a sensor of organelle dysfunction

Diverse pathogen- and damage-associated stresses drive inflammation via activation of the multimolecular NLRP3–inflammasome complex. How the effects of diverse stimuli are integrated by the cell to regulate NLRP3 has been the subject of intense research, and yet an accepted unifying hypothesis for t...

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Bibliographische Detailangaben
Veröffentlicht in:J Cell Biol
Hauptverfasser: Seoane, Paula I., Lee, Bali, Hoyle, Christopher, Yu, Shi, Lopez-Castejon, Gloria, Lowe, Martin, Brough, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: Rockefeller University Press 2020
Schlagworte:
Review
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7543090/
https://ncbi.nlm.nih.gov/pubmed/33044555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202006194
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