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The NLRP3–inflammasome as a sensor of organelle dysfunction

Diverse pathogen- and damage-associated stresses drive inflammation via activation of the multimolecular NLRP3–inflammasome complex. How the effects of diverse stimuli are integrated by the cell to regulate NLRP3 has been the subject of intense research, and yet an accepted unifying hypothesis for t...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Cell Biol
Auteurs principaux: Seoane, Paula I., Lee, Bali, Hoyle, Christopher, Yu, Shi, Lopez-Castejon, Gloria, Lowe, Martin, Brough, David
Format: Artigo
Langue:Inglês
Publié: Rockefeller University Press 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7543090/
https://ncbi.nlm.nih.gov/pubmed/33044555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202006194
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