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The NLRP3–inflammasome as a sensor of organelle dysfunction

Diverse pathogen- and damage-associated stresses drive inflammation via activation of the multimolecular NLRP3–inflammasome complex. How the effects of diverse stimuli are integrated by the cell to regulate NLRP3 has been the subject of intense research, and yet an accepted unifying hypothesis for t...

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Bibliografski detalji
Izdano u:J Cell Biol
Glavni autori: Seoane, Paula I., Lee, Bali, Hoyle, Christopher, Yu, Shi, Lopez-Castejon, Gloria, Lowe, Martin, Brough, David
Format: Artigo
Jezik:Inglês
Izdano: Rockefeller University Press 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7543090/
https://ncbi.nlm.nih.gov/pubmed/33044555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202006194
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