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Mechanisms of NLRP3 priming in inflammaging and age related diseases

The NLRP3 inflammasome is a vital part of the innate immune response, whilst its aberrant activation drives the progression of a number of non-communicable diseases. Thus, NLRP3 inflammasome assembly must be tightly controlled at several checkpoints. The priming step of NLRP3 inflammasome activation...

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Veröffentlicht in:Cytokine Growth Factor Rev
Hauptverfasser: Gritsenko, Anna, Green, Jack P., Brough, David, Lopez-Castejon, Gloria
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier Science 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7571497/
https://ncbi.nlm.nih.gov/pubmed/32883606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cytogfr.2020.08.003
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