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Dynamics of Staphylococcus aureus Cas9 in DNA target Association and Dissociation
Staphylococcus aureus Cas9 (SaCas9) is an RNA‐guided endonuclease that targets complementary DNA adjacent to a protospacer adjacent motif (PAM) for cleavage. Its small size facilitates in vivo delivery for genome editing in various organisms. Herein, using single‐molecule and ensemble approaches, we...
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| Publicado no: | EMBO Rep |
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| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7534634/ https://ncbi.nlm.nih.gov/pubmed/32790142 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.202050184 |
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