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In vivo genome editing using Staphylococcus aureus Cas9
The RNA-guided endonuclease Cas9 has emerged as a versatile genome-editing platform. However, the size of the commonly used Cas9 from Streptococcus pyogenes (SpCas9) limits its utility for basic research and therapeutic applications that employ the highly versatile adeno-associated virus (AAV) deliv...
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| Pubblicato in: | Nature |
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| Autori principali: | , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4393360/ https://ncbi.nlm.nih.gov/pubmed/25830891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14299 |
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