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Staphylococcus aureus Cas9 is a multiple-turnover enzyme
Cas9 nuclease is the key effector of type II CRISPR adaptive immune systems found in bacteria. The nuclease can be programmed by a single guide RNA (sgRNA) to cleave DNA in a sequence-specific manner. This property has led to its widespread adoption as a genome editing tool in research laboratories...
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| Опубликовано в: : | RNA |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Cold Spring Harbor Laboratory Press
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6298560/ https://ncbi.nlm.nih.gov/pubmed/30348755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.067355.118 |
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