An evolutionarily ancient mechanism for regulation of hemoglobin expression in vertebrate red cells

The oxygen transport function of hemoglobin (HB) is thought to have arisen ∼500 million years ago, roughly coinciding with the divergence between jawless (Agnatha) and jawed (Gnathostomata) vertebrates. Intriguingly, extant HBs of jawless and jawed vertebrates were shown to have evolved twice, and i...

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Dades bibliogràfiques
Publicat a:Blood
Autors principals: Miyata, Masato, Gillemans, Nynke, Hockman, Dorit, Demmers, Jeroen A. A., Cheng, Jan-Fang, Hou, Jun, Salminen, Matti, Fisher, Christopher A., Taylor, Stephen, Gibbons, Richard J., Ganis, Jared J., Zon, Leonard I., Grosveld, Frank, Mulugeta, Eskeatnaf, Sauka-Spengler, Tatjana, Higgs, Douglas R., Philipsen, Sjaak
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2020
Matèries:
Plenary Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7531998/
https://ncbi.nlm.nih.gov/pubmed/32396940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020004826
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