An evolutionarily ancient mechanism for regulation of hemoglobin expression in vertebrate red cells

The oxygen transport function of hemoglobin (HB) is thought to have arisen ∼500 million years ago, roughly coinciding with the divergence between jawless (Agnatha) and jawed (Gnathostomata) vertebrates. Intriguingly, extant HBs of jawless and jawed vertebrates were shown to have evolved twice, and i...

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Bibliografische gegevens
Gepubliceerd in:Blood
Hoofdauteurs: Miyata, Masato, Gillemans, Nynke, Hockman, Dorit, Demmers, Jeroen A. A., Cheng, Jan-Fang, Hou, Jun, Salminen, Matti, Fisher, Christopher A., Taylor, Stephen, Gibbons, Richard J., Ganis, Jared J., Zon, Leonard I., Grosveld, Frank, Mulugeta, Eskeatnaf, Sauka-Spengler, Tatjana, Higgs, Douglas R., Philipsen, Sjaak
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Hematology 2020
Onderwerpen:
Plenary Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7531998/
https://ncbi.nlm.nih.gov/pubmed/32396940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020004826
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