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The Gene-Regulatory Footprint of Aging Highlights Conserved Central Regulators
Many genes and pathways have been linked to aging, yet our understanding of underlying molecular mechanisms is still lacking. Here, we measure changes in the transcriptome, histone modifications, and DNA methylome in three metabolic tissues of adult and aged mice. Transcriptome and methylome changes...
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| 發表在: | Cell Rep |
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| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Cell Press
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7527782/ https://ncbi.nlm.nih.gov/pubmed/32997995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108203 |
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