A polymorphism in the cachexia-associated gene INHBA predicts efficacy of regorafenib in patients with refractory metastatic colorectal cancer

Activin/myostatin signaling has a critical role not only in cachexia but also in tumor angiogenesis. Cachexia is a frequent complication among patients with advanced cancer and heavily pretreated patients. We aimed to evaluate the prognostic significance of cachexia-associated genetic variants in re...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Miyamoto, Yuji, Schirripa, Marta, Suenaga, Mitsukuni, Cao, Shu, Zhang, Wu, Okazaki, Satoshi, Berger, Martin D., Matsusaka, Satoshi, Yang, Dongyun, Ning, Yan, Baba, Hideo, Loupakis, Fotios, Lonardi, Sara, Pietrantonio, Filippo, Borelli, Beatrice, Cremolini, Chiara, Yamaguchi, Toshiharu, Lenz, Heinz-Josef
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7514061/
https://ncbi.nlm.nih.gov/pubmed/32970737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0239439
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