Single Nucleotide Polymorphisms in MiRNA Binding Sites of Nucleotide Excision Repair-Related Genes Predict Clinical Benefit of Oxaliplatin in FOLFOXIRI Plus Bevacizumab: Analysis of the TRIBE Trial

Background: The nucleotide excision repair (NER) pathway participates in platinum-induced DNA damage repair. Single nucleotide polymorphisms (SNPs) in miRNA-binding sites in the NER genes RPA2 and GTF2H1 are associated with the risk of colorectal cancer (CRC). Here, we analyzed whether RPA2 and GTF2...

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Udgivet i:Cancers (Basel)
Main Authors: Suenaga, Mitsukuni, Schirripa, Marta, Cao, Shu, Zhang, Wu, Yang, Dongyun, Cremolini, Chiara, Murgioni, Sabina, Lonardi, Sara, Ning, Yan, Okazaki, Satoshi, Berger, Martin D., Miyamoto, Yuji, Barzi, Afsaneh, Loupakis, Fotios, Falcone, Alfredo, Lenz, Heinz-Josef
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7408001/
https://ncbi.nlm.nih.gov/pubmed/32629861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12071742
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