Gene Polymorphisms in the CCL5/CCR5 Pathway as a Genetic Biomarker for Outcome and Hand–Foot Skin Reaction in Metastatic Colorectal Cancer Patients Treated With Regorafenib

Regorafenib confers the benefit of longer survival in metastatic colorectal cancer patients. The CCL5/CCR5 pathway modulates endothelial progenitor cell migration and vascular endothelial growth factor A production. Genetic variants of CCL4 and CCL3 may predict outcomes, and the different frequencie...

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Detalhes bibliográficos
Publicado no:Clin Colorectal Cancer
Main Authors: Suenaga, Mitsukuni, Schirripa, Marta, Cao, Shu, Zhang, Wu, Yang, Dongyun, Ning, Yan, Cremolini, Chiara, Antoniotti, Carlotta, Borelli, Beatrice, Mashima, Tetsuo, Okazaki, Satoshi, Berger, Martin D., Miyamoto, Yuji, Gopez, Roel, Barzi, Afsaneh, Lonardi, Sara, Yamaguchi, Toshiharu, Falcone, Alfredo, Loupakis, Fotios, Lenz, Heinz-Josef
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7493703/
https://ncbi.nlm.nih.gov/pubmed/29606345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clcc.2018.02.010
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