Potential Molecular Cross Talk Among CCR5 Pathway Predicts Regorafenib Responsiveness in Metastatic Colorectal Cancer Patients

Background: Genetic variants in the CCL5/CCR5 pathway have been shown to predict regorafenib efficacy in patients with metastatic colorectal cancer (mCRC). This study investigated the biological role of CCL4 and CCL3 gene polymorphisms in patients with refractory mCRC treated using regorafenib. Pati...

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Detalhes bibliográficos
Publicado no:Cancer Genomics Proteomics
Main Authors: SUENAGA, MITSUKUNI, ZHANG, WU, MASHIMA, TETSUO, SCHIRRIPA, MARTA, CAO, SHU, OKAZAKI, SATOSHI, BERGER, MARTIN D., MIYAMOTO, YUJI, BARZI, AFSANEH, YAMAGUCHI, TOSHIHARU, LENZ, HEINZ-JOSEF
Formato: Artigo
Idioma:Inglês
Publicado em: International Institute of Anticancer Research 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8126324/
https://ncbi.nlm.nih.gov/pubmed/33893084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21873/cgp.20262
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