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Potential Molecular Cross Talk Among CCR5 Pathway Predicts Regorafenib Responsiveness in Metastatic Colorectal Cancer Patients

Background: Genetic variants in the CCL5/CCR5 pathway have been shown to predict regorafenib efficacy in patients with metastatic colorectal cancer (mCRC). This study investigated the biological role of CCL4 and CCL3 gene polymorphisms in patients with refractory mCRC treated using regorafenib. Pati...

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Publicat a:Cancer Genomics Proteomics
Autors principals: SUENAGA, MITSUKUNI, ZHANG, WU, MASHIMA, TETSUO, SCHIRRIPA, MARTA, CAO, SHU, OKAZAKI, SATOSHI, BERGER, MARTIN D., MIYAMOTO, YUJI, BARZI, AFSANEH, YAMAGUCHI, TOSHIHARU, LENZ, HEINZ-JOSEF
Format: Artigo
Idioma:Inglês
Publicat: International Institute of Anticancer Research 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8126324/
https://ncbi.nlm.nih.gov/pubmed/33893084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21873/cgp.20262
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