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Chemical strategies to overcome resistance against targeted anticancer therapeutics

Emergence of resistance is a major factor limiting the efficacy of molecularly targeted anticancer drugs. Understanding the specific mutations, or other genetic or cellular changes, that confer drug resistance can help in the development of therapeutic strategies with improved efficacies. Here, we o...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Chem Biol
Prif Awduron: Pisa, Rudolf, Kapoor, Tarun M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7510053/
https://ncbi.nlm.nih.gov/pubmed/32694636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-020-0596-8
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