A Polymorphism within the Vitamin D Transporter Gene Predicts Outcome in Metastatic Colorectal Cancer Patients Treated with FOLFIRI/Bevacizumab or FOLFIRI/Cetuximab

PURPOSE: Vitamin D exerts its inhibitory influence on colon cancer growth by inhibiting Wnt signaling and angiogenesis. We hypothesized that SNPs in genes involved in vitamin D transport, metabolism, and signaling are associated with outcome in metastatic colorectal cancer (mCRC) patients treated wi...

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Gepubliceerd in:Clin Cancer Res
Hoofdauteurs: Berger, Martin D., Stintzing, Sebastian, Heinemann, Volker, Cao, Shu, Yang, Dongyun, Sunakawa, Yu, Matsusaka, Satoshi, Ning, Yan, Okazaki, Satoshi, Miyamoto, Yuji, Suenaga, Mitsukuni, Schirripa, Marta, Hanna, Diana L., Soni, Shivani, Puccini, Alberto, Zhang, Wu, Cremolini, Chiara, Falcone, Alfredo, Loupakis, Fotios, Lenz, Heinz-Josef
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7505162/
https://ncbi.nlm.nih.gov/pubmed/29208668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-1663
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