A Polymorphism within the Vitamin D Transporter Gene Predicts Outcome in Metastatic Colorectal Cancer Patients Treated with FOLFIRI/Bevacizumab or FOLFIRI/Cetuximab

PURPOSE: Vitamin D exerts its inhibitory influence on colon cancer growth by inhibiting Wnt signaling and angiogenesis. We hypothesized that SNPs in genes involved in vitamin D transport, metabolism, and signaling are associated with outcome in metastatic colorectal cancer (mCRC) patients treated wi...

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發表在:Clin Cancer Res
Main Authors: Berger, Martin D., Stintzing, Sebastian, Heinemann, Volker, Cao, Shu, Yang, Dongyun, Sunakawa, Yu, Matsusaka, Satoshi, Ning, Yan, Okazaki, Satoshi, Miyamoto, Yuji, Suenaga, Mitsukuni, Schirripa, Marta, Hanna, Diana L., Soni, Shivani, Puccini, Alberto, Zhang, Wu, Cremolini, Chiara, Falcone, Alfredo, Loupakis, Fotios, Lenz, Heinz-Josef
格式: Artigo
語言:Inglês
出版: 2017
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7505162/
https://ncbi.nlm.nih.gov/pubmed/29208668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-1663
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