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Clinical significance of TLR1 I602S polymorphism for patients with metastatic colorectal cancer treated with FOLFIRI plus bevacizumab

The purpose of this study was to evaluate the clinical significance of single nucleotide polymorphisms in TLR1, TLR2, TLR6, and TAK1 in patients with metastatic colorectal cancer (mCRC). We genotyped 9 SNPs of TLR1, TLR2, TLR6, and TAK1 in mCRC patients treated with 1st-line FOLFIRI (combination the...

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Detalhes bibliográficos
Publicado no:Mol Cancer Ther
Main Authors: Okazaki, Satoshi, Loupakis, Fotios, Stintzing, Sebastian, Cao, Shu, Zhang, Wu, Yang, Dongyun, Ning, Yan, Sunakawa, Yu, Stremitzer, Stefan, Matsusaka, Satoshi, Berger, Martin D., Parekh, Anish, West, Jordan D., Miyamoto, Yuji, Suenaga, Mitsukuni, Schirripa, Marta, Cremolini, Chiara, Falcone, Alfredo, Heinemann, Volker, DePaolo, R. William, Lenz, Heinz-Josef
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936942/
https://ncbi.nlm.nih.gov/pubmed/27196764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-15-0931
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