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Constitutive Activity in the Angiotensin II Type 1 Receptor: Discovery and Applications

The pathophysiological actions of the renin–angiotensin system hormone, angiotensin II (AngII), are mainly mediated by the AngII type 1 (AT1) receptor, a GPCR. The intrinsic spontaneous activity of the AT1 receptor in native tissues is difficult to detect due to its low expression levels. However, f...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Adv Pharmacol
Prif Awduron: Unal, Hamiyet, Karnik, Sadashiva S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7500102/
https://ncbi.nlm.nih.gov/pubmed/24931196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-417197-8.00006-7
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