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Current Topics in Angiotensin II Type 1 Receptor Research: Focus on Inverse Agonism, Receptor Dimerization and Biased Agonism

Although the octapeptide hormone angiotensin II (Ang II) regulates cardiovascular and renal homeostasis through the Ang II type 1 receptor (AT1R), overstimulation of AT1R causes various human diseases, such as hypertension and cardiac hypertrophy. Therefore, AT1R blockers (ARBs) have been widely use...

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Detalhes bibliográficos
Publicado no:Pharmacol Res
Main Authors: Takezako, Takanobu, Unal, Hamiyet, Karnik, Sadashiva S, Node, Koichi
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567726/
https://ncbi.nlm.nih.gov/pubmed/28648738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2017.06.013
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