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Constitutive Activity in the Angiotensin II Type 1 Receptor: Discovery and Applications
The pathophysiological actions of the renin–angiotensin system hormone, angiotensin II (AngII), are mainly mediated by the AngII type 1 (AT1) receptor, a GPCR. The intrinsic spontaneous activity of the AT1 receptor in native tissues is difficult to detect due to its low expression levels. However, f...
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| Опубликовано в: : | Adv Pharmacol |
|---|---|
| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7500102/ https://ncbi.nlm.nih.gov/pubmed/24931196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-417197-8.00006-7 |
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