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Ligand-specific Conformation of Extracellular Loop-2 in the Angiotensin II Type 1 Receptor

The orientation of the second extracellular loop (ECL2) is divergent in G-protein coupled receptor (GPCR) structures determined. This discovery provoked the question, is the ECL2 conformation differentially regulated in the GPCRs that respond to diffusible ligands? We have determined the conformatio...

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書誌詳細
主要な著者: Unal, Hamiyet, Jagannathan, Rajaganapathi, Bhat, Manjunatha B., Karnik, Sadashiva S.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871501/
https://ncbi.nlm.nih.gov/pubmed/20299456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.094870
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