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Ligand-specific Conformation of Extracellular Loop-2 in the Angiotensin II Type 1 Receptor
The orientation of the second extracellular loop (ECL2) is divergent in G-protein coupled receptor (GPCR) structures determined. This discovery provoked the question, is the ECL2 conformation differentially regulated in the GPCRs that respond to diffusible ligands? We have determined the conformatio...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2871501/ https://ncbi.nlm.nih.gov/pubmed/20299456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.094870 |
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