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Enantioselective Synthesis of 3‐Fluorochromanes via Iodine(I)/Iodine(III) Catalysis

The chromane nucleus is common to a plenum of bioactive small molecules where it is frequently oxidized at position 3. Motivated by the importance of this position in conferring efficacy, and the prominence of bioisosterism in drug discovery, an iodine(I)/iodine(III) catalysis strategy to access ena...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Sarie, Jérôme C., Thiehoff, Christian, Neufeld, Jessica, Daniliuc, Constantin G., Gilmour, Ryan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7496101/
https://ncbi.nlm.nih.gov/pubmed/32347605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202005181
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