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Enantioselective Synthesis of 3‐Fluorochromanes via Iodine(I)/Iodine(III) Catalysis

The chromane nucleus is common to a plenum of bioactive small molecules where it is frequently oxidized at position 3. Motivated by the importance of this position in conferring efficacy, and the prominence of bioisosterism in drug discovery, an iodine(I)/iodine(III) catalysis strategy to access ena...

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Bibliografiske detaljer
Udgivet i:Angew Chem Int Ed Engl
Main Authors: Sarie, Jérôme C., Thiehoff, Christian, Neufeld, Jessica, Daniliuc, Constantin G., Gilmour, Ryan
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7496101/
https://ncbi.nlm.nih.gov/pubmed/32347605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202005181
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