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Deciphering the role of distinct DNA-PK phosphorylations at collapsed replication forks.
It has recently been established that the marked sensitivity of ATM deficient cells to topoisomerase poisons like camptothecin (Cpt) results from unrestrained end-joining of DNA ends at collapsed replication forks that is mediated by the non-homologous end joining [NHEJ] pathway and results in the i...
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| Publié dans: | DNA Repair (Amst) |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7494621/ https://ncbi.nlm.nih.gov/pubmed/32674014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2020.102925 |
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