CDK1 phosphorylates WRN at collapsed replication forks

Regulation of end-processing is critical for accurate repair and to switch between homologous recombination (HR) and non-homologous end joining (NHEJ). End resection is a two-stage process but very little is known about regulation of the long-range resection, especially in humans. WRN participates i...

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Udgivet i:Nat Commun
Main Authors: Palermo, Valentina, Rinalducci, Sara, Sanchez, Massimo, Grillini, Francesca, Sommers, Joshua A., Brosh, Robert M., Zolla, Lello, Franchitto, Annapaola, Pichierri, Pietro
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5028418/
https://ncbi.nlm.nih.gov/pubmed/27634057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12880
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