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Deciphering phenotypic variance in different models of DNA-PKcs deficiency.
DNA-PKcs deficiency has been studied in numerous animal models and cell culture systems. In previous studies of kinase inactivating mutations in cell culture systems, ablation of DNA-PK’s catalytic activity results in a cell phenotype that is virtually indistinguishable from that ascribed to complet...
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| Veröffentlicht in: | DNA Repair (Amst) |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6312468/ https://ncbi.nlm.nih.gov/pubmed/30409670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2018.10.004 |
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