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The leucine rich region of DNA-PKcs contributes to its innate DNA affinity
DNA-PK is a protein complex that consists of a DNA-binding, regulatory subunit [Ku] and a larger ∼465 kDa catalytic subunit [DNA-PKcs], a serine/threonine protein kinase. The kinase activity of DNA-PKcs resides between residues 3745 and 4013, a PI3 kinase domain. Another recognized domain within thi...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1310895/ https://ncbi.nlm.nih.gov/pubmed/16340007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki990 |
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