Inhibition of homologous recombination by variants of the catalytic subunit of the DNA-dependent protein kinase (DNA-PKcs)

Two major DNA double-strand break repair pathways exist in all eukaryotes, nonhomologous DNA end joining (NHEJ) and homologous recombination (HR). Although both pathways can function throughout the cell cycle, NHEJ predominates in G(0)/G(1) (when a replicated sister chromatid is unavailable), wherea...

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Detalhes bibliográficos
Main Authors: Convery, Erin, Shin, Euy Kyun, Ding, Qi, Wang, Wei, Douglas, Pauline, Davis, Laurie S., Nickoloff, Jac A., Lees-Miller, Susan P., Meek, Katheryn
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC547837/
https://ncbi.nlm.nih.gov/pubmed/15668400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406466102
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