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Choosing the right path: does DNA-PK help make the decision?

DNA double-strand breaks are extremely harmful lesions that can lead to genomic instability and cell death if not properly repaired. There are at least three pathways that are responsible for repairing DNA double-strand breaks in mammalian cells: non-homologous end joining, homologous recombination...

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Detalhes bibliográficos
Main Authors: Neal, Jessica A., Meek, Katheryn
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109507/
https://ncbi.nlm.nih.gov/pubmed/21376743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2011.02.010
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