ATR phosphorylates SMARCAL1 to prevent replication fork collapse

The DNA damage response kinase ataxia telangiectasia and Rad3-related (ATR) coordinates much of the cellular response to replication stress. The exact mechanisms by which ATR regulates DNA synthesis in conditions of replication stress are largely unknown, but this activity is critical for the viabil...

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Main Authors: Couch, Frank B., Bansbach, Carol E., Driscoll, Robert, Luzwick, Jessica W., Glick, Gloria G., Bétous, Rémy, Carroll, Clinton M., Jung, Sung Yun, Qin, Jun, Cimprich, Karlene A., Cortez, David
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2013
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731549/
https://ncbi.nlm.nih.gov/pubmed/23873943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.214080.113
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