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ATR phosphorylates SMARCAL1 to prevent replication fork collapse
The DNA damage response kinase ataxia telangiectasia and Rad3-related (ATR) coordinates much of the cellular response to replication stress. The exact mechanisms by which ATR regulates DNA synthesis in conditions of replication stress are largely unknown, but this activity is critical for the viabil...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Cold Spring Harbor Laboratory Press
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3731549/ https://ncbi.nlm.nih.gov/pubmed/23873943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.214080.113 |
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