ATR phosphorylates SMARCAL1 to prevent replication fork collapse

The DNA damage response kinase ataxia telangiectasia and Rad3-related (ATR) coordinates much of the cellular response to replication stress. The exact mechanisms by which ATR regulates DNA synthesis in conditions of replication stress are largely unknown, but this activity is critical for the viabil...

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Bibliografiske detaljer
Main Authors: Couch, Frank B., Bansbach, Carol E., Driscoll, Robert, Luzwick, Jessica W., Glick, Gloria G., Bétous, Rémy, Carroll, Clinton M., Jung, Sung Yun, Qin, Jun, Cimprich, Karlene A., Cortez, David
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2013
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731549/
https://ncbi.nlm.nih.gov/pubmed/23873943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.214080.113
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