Ageing compromises mouse thymus function and remodels epithelial cell differentiation

Ageing is characterised by cellular senescence, leading to imbalanced tissue maintenance, cell death and compromised organ function. This is first observed in the thymus, the primary lymphoid organ that generates and selects T cells. However, the molecular and cellular mechanisms underpinning these...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:eLife
Main Authors: Baran-Gale, Jeanette, Morgan, Michael D, Maio, Stefano, Dhalla, Fatima, Calvo-Asensio, Irene, Deadman, Mary E, Handel, Adam E, Maynard, Ashley, Chen, Steven, Green, Foad, Sit, Rene V, Neff, Norma F, Darmanis, Spyros, Tan, Weilun, May, Andy P, Marioni, John C, Ponting, Chris P, Holländer, Georg A
פורמט: Artigo
שפה:Inglês
יצא לאור: eLife Sciences Publications, Ltd 2020
נושאים:
Immunology and Inflammation
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7490013/
https://ncbi.nlm.nih.gov/pubmed/32840480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.56221
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים