Ageing compromises mouse thymus function and remodels epithelial cell differentiation

Ageing is characterised by cellular senescence, leading to imbalanced tissue maintenance, cell death and compromised organ function. This is first observed in the thymus, the primary lymphoid organ that generates and selects T cells. However, the molecular and cellular mechanisms underpinning these...

詳細記述

保存先:
書誌詳細
出版年:eLife
主要な著者: Baran-Gale, Jeanette, Morgan, Michael D, Maio, Stefano, Dhalla, Fatima, Calvo-Asensio, Irene, Deadman, Mary E, Handel, Adam E, Maynard, Ashley, Chen, Steven, Green, Foad, Sit, Rene V, Neff, Norma F, Darmanis, Spyros, Tan, Weilun, May, Andy P, Marioni, John C, Ponting, Chris P, Holländer, Georg A
フォーマット: Artigo
言語:Inglês
出版事項: eLife Sciences Publications, Ltd 2020
主題:
Immunology and Inflammation
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7490013/
https://ncbi.nlm.nih.gov/pubmed/32840480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.56221
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料