The Alzheimer’s disease-associated protective Plcγ2-P522R variant promotes immune functions

BACKGROUND: Microglia-specific genetic variants are enriched in several neurodegenerative diseases, including Alzheimer’s disease (AD), implicating a central role for alterations of the innate immune system in the disease etiology. A rare coding variant in the PLCG2 gene (rs72824905, p.P522R) expres...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Neurodegener
Egile Nagusiak: Takalo, Mari, Wittrahm, Rebekka, Wefers, Benedikt, Parhizkar, Samira, Jokivarsi, Kimmo, Kuulasmaa, Teemu, Mäkinen, Petra, Martiskainen, Henna, Wurst, Wolfgang, Xiang, Xianyuan, Marttinen, Mikael, Poutiainen, Pekka, Haapasalo, Annakaisa, Hiltunen, Mikko, Haass, Christian
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2020
Gaiak:
Short Report
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7488484/
https://ncbi.nlm.nih.gov/pubmed/32917267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-020-00402-7
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak