Altered Insulin Signaling in Alzheimer’s Disease Brain – Special Emphasis on PI3K-Akt Pathway

Alzheimer’s disease (AD) and type 2 diabetes (T2D) are both diseases with increasing prevalence in aging populations. T2D, characterized by insulin resistance and defective insulin signaling, is a common co-morbidity and a risk factor for AD, increasing the risk approximately two to fourfold. Insuli...

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Detalles Bibliográficos
Publicado en:Front Neurosci
Autores principales: Gabbouj, Sami, Ryhänen, Simo, Marttinen, Mikael, Wittrahm, Rebekka, Takalo, Mari, Kemppainen, Susanna, Martiskainen, Henna, Tanila, Heikki, Haapasalo, Annakaisa, Hiltunen, Mikko, Natunen, Teemu
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591470/
https://ncbi.nlm.nih.gov/pubmed/31275108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2019.00629
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