Molecular Mechanisms of Synaptotoxicity and Neuroinflammation in Alzheimer’s Disease

Alzheimer’s disease (AD) is the most common neurodegenerative disorder, which is clinically associated with a global cognitive decline and progressive loss of memory and reasoning. According to the prevailing amyloid cascade hypothesis of AD, increased soluble amyloid-β (Aβ) oligomer levels impair t...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Marttinen, Mikael, Takalo, Mari, Natunen, Teemu, Wittrahm, Rebekka, Gabbouj, Sami, Kemppainen, Susanna, Leinonen, Ville, Tanila, Heikki, Haapasalo, Annakaisa, Hiltunen, Mikko
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6301995/
https://ncbi.nlm.nih.gov/pubmed/30618585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00963
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