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Oncogenic gene expression programs in leiomyosarcoma and characterization of conventional, inflammatory and uterogenic subtypes

Leiomyosarcoma (LMS) is a mesenchymal neoplasm with complex copy number alterations and characteristic loss of tumor suppressor genes without known recurrent activating mutations. Clinical management of advanced LMS relies on chemotherapy and complementary palliative approaches, and research efforts...

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Détails bibliographiques
Publié dans:Mol Cancer Res
Auteurs principaux: Hemming, Matthew L., Fan, Changyu, Raut, Chandrajit P., Demetri, George D., Armstrong, Scott A., Sicinska, Ewa, George, Suzanne
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7484251/
https://ncbi.nlm.nih.gov/pubmed/32518213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-20-0197
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