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Oncogenic gene expression programs in leiomyosarcoma and characterization of conventional, inflammatory and uterogenic subtypes

Leiomyosarcoma (LMS) is a mesenchymal neoplasm with complex copy number alterations and characteristic loss of tumor suppressor genes without known recurrent activating mutations. Clinical management of advanced LMS relies on chemotherapy and complementary palliative approaches, and research efforts...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cancer Res
Hauptverfasser: Hemming, Matthew L., Fan, Changyu, Raut, Chandrajit P., Demetri, George D., Armstrong, Scott A., Sicinska, Ewa, George, Suzanne
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7484251/
https://ncbi.nlm.nih.gov/pubmed/32518213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-20-0197
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