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Isolation and characterization of antibody fragment selective for human AD brain derived tau variants

Reagents that can selectively recognize specific toxic tau variants associated with onset and progression of AD and other tauopathies can be effective diagnostic and therapeutic tools. We utilized a novel atomic force microscopy (AFM) based biopanning protocol to isolate antibody fragments (scFvs) t...

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Publicat a:Neurobiol Aging
Autors principals: Venkataraman, Lalitha, He, Ping, Schulz, Philip, Sierks, Michael R.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7484196/
https://ncbi.nlm.nih.gov/pubmed/32497877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2020.04.014
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