Isolation and characterization of antibody fragments selective for human FTD brain derived TDP-43 variants

BACKGROUND: Frontotemporal dementia (FTD) is the second leading cause of early onset dementia following Alzheimer’s disease. It involves atrophy of the frontal and temporal regions of the brain affecting language, memory, and behavior. Transactive response DNA-binding protein 43 (TDP-43) pathology i...

Full description

Saved in:
Bibliographic Details
Published in:BMC Neurosci
Main Authors: Venkataraman, Lalitha, He, Ping, Khan, Galam, Harris, Brent T., Sierks, Michael R.
Format: Artigo
Language:Inglês
Published: BioMed Central 2020
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7472585/
https://ncbi.nlm.nih.gov/pubmed/32887544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-020-00586-0
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items