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TDP-43 protein variants as biomarkers in amyotrophic lateral sclerosis

BACKGROUND: TDP-43 aggregates accumulate in individuals affected by amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases, representing potential diagnostic and therapeutic targets. Using an atomic force microscopy based biopanning protocol developed in our lab, we previously isol...

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Detalhes bibliográficos
Publicado no:BMC Neurosci
Main Authors: Williams, Stephanie M., Khan, Galam, Harris, Brent T., Ravits, John, Sierks, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5264476/
https://ncbi.nlm.nih.gov/pubmed/28122516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-017-0334-7
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