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TDP-43—The key to understanding amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that causes motor neuron degeneration leading to progressive muscle atrophy, weakness, paralysis and death. The majority of ALS (>95%) shows intracellular aggregation of transactive response DNA binding protein (TDP-43) as a...
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| Published in: | Rare Dis |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Taylor & Francis
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4755248/ https://ncbi.nlm.nih.gov/pubmed/26942097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21675511.2014.944443 |
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