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TDP-43—The key to understanding amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that causes motor neuron degeneration leading to progressive muscle atrophy, weakness, paralysis and death. The majority of ALS (>95%) shows intracellular aggregation of transactive response DNA binding protein (TDP-43) as a...

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Detalhes bibliográficos
Publicado no:Rare Dis
Main Authors: Xu, Zuoshang, Yang, Chunxing
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755248/
https://ncbi.nlm.nih.gov/pubmed/26942097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21675511.2014.944443
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