Partial loss of TDP-43 function causes phenotypes of amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a fatal neurological disease that causes motor neuron degeneration, progressive motor dysfunction, paralysis, and death. Although multiple causes have been identified for this disease, >95% of ALS cases show aggregation of transactive response DNA binding pr...

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Detalhes bibliográficos
Main Authors: Yang, Chunxing, Wang, Hongyan, Qiao, Tao, Yang, Bin, Aliaga, Leonardo, Qiu, Linghua, Tan, Weijia, Salameh, Johnny, McKenna-Yasek, Diane M., Smith, Thomas, Peng, Lingtao, Moore, Melissa J., Brown, Robert H., Cai, Huaibin, Xu, Zuoshang
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3970502/
https://ncbi.nlm.nih.gov/pubmed/24616503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1322641111
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