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Isolation and characterization of antibody fragment selective for human AD brain derived tau variants

Reagents that can selectively recognize specific toxic tau variants associated with onset and progression of AD and other tauopathies can be effective diagnostic and therapeutic tools. We utilized a novel atomic force microscopy (AFM) based biopanning protocol to isolate antibody fragments (scFvs) t...

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Bibliografski detalji
Izdano u:Neurobiol Aging
Glavni autori: Venkataraman, Lalitha, He, Ping, Schulz, Philip, Sierks, Michael R.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7484196/
https://ncbi.nlm.nih.gov/pubmed/32497877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2020.04.014
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