Somatic Mutations and Clonal Hematopoiesis in Aplastic Anemia

BACKGROUND: In acquired aplastic anemia, the immune system destroys hematopoietic cells, leading to pancytopenia. Patients respond to immunosuppressive therapy but about 15 per cent develop myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML), usually many months to years after diagnosis...

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書誌詳細
出版年:N Engl J Med
主要な著者: Yoshizato, Tetsuichi, Dumitriu, Bogdan, Hosokawa, Kohei, Makishima, Hideki, Yoshida, Kenichi, Townsley, Danielle, Sato-Otsubo, Aiko, Sato, Yusuke, Liu, Delong, Suzuki, Hiromichi, Wu, Colin O., Shiraishi, Yuichi, Clemente, Michael J., Kataoka, Keisuke, Shiozawa, Yusuke, Okuno, Yusuke, Chiba, Kenichi, Tanaka, Hiroko, Nagata, Yasunobu, Katagiri, Takamasa, Kon, Ayana, Sanada, Masashi, Scheinberg, Phillip, Miyano, Satoru, Maciejewski, Jaroslaw P., Nakao, Shinji, Young, Neal S., Ogawa, Seishi
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7478337/
https://ncbi.nlm.nih.gov/pubmed/26132940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1414799
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