Somatic Mutations and Clonal Hematopoiesis in Aplastic Anemia

BACKGROUND: In acquired aplastic anemia, the immune system destroys hematopoietic cells, leading to pancytopenia. Patients respond to immunosuppressive therapy but about 15 per cent develop myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML), usually many months to years after diagnosis...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :N Engl J Med
Главные авторы: Yoshizato, Tetsuichi, Dumitriu, Bogdan, Hosokawa, Kohei, Makishima, Hideki, Yoshida, Kenichi, Townsley, Danielle, Sato-Otsubo, Aiko, Sato, Yusuke, Liu, Delong, Suzuki, Hiromichi, Wu, Colin O., Shiraishi, Yuichi, Clemente, Michael J., Kataoka, Keisuke, Shiozawa, Yusuke, Okuno, Yusuke, Chiba, Kenichi, Tanaka, Hiroko, Nagata, Yasunobu, Katagiri, Takamasa, Kon, Ayana, Sanada, Masashi, Scheinberg, Phillip, Miyano, Satoru, Maciejewski, Jaroslaw P., Nakao, Shinji, Young, Neal S., Ogawa, Seishi
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7478337/
https://ncbi.nlm.nih.gov/pubmed/26132940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1414799
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы